Hmdb loader
Identification
HMDB Protein ID HMDBP12791
Secondary Accession Numbers None
Name Cell division cycle-associated 7-like protein
Synonyms
  1. Protein JPO2
  2. Transcription factor RAM2
Gene Name CDCA7L
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Pathways Not Available
Reactions Not Available
GO Classification
Biological Process
positive regulation of cell proliferation
regulation of transcription, DNA-dependent
Cellular Component
cytosol
nucleolus
nucleus
nucleoplasm
fibrillar center
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 454
Molecular Weight 52205.695
Theoretical pI 5.74
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q96GN5
UniProtKB/Swiss-Prot Entry Name CDA7L_HUMAN
PDB IDs
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
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