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Showing Protein 1-deoxy-D-xylulose 5-phosphate reductoisomerase (HMDBP12264)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 metabolite
Identification
HMDB Protein ID HMDBP12264
Secondary Accession Numbers None
Name 1-deoxy-D-xylulose 5-phosphate reductoisomerase
Synonyms
  1. DXP reductoisomerase
  2. 1-deoxyxylulose-5-phosphate reductoisomerase
  3. 2-C-methyl-D-erythritol 4-phosphate synthase
Gene Name DXR
Protein Type Unknown
Biological Properties
General Function Not Available
Specific Function Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
Pathways
  • Biosynthesis of secondary metabolites
  • isopentenyl diphosphate biosynthesis via DXP pathway
  • Terpenoid backbone biosynthesis
Reactions Not Available
GO Classification
Biological Process
isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
terpenoid biosynthetic process
Molecular Function
metal ion binding
1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NADPH binding
Cellular Location Not Available
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence Not Available
Protein Properties
Number of Residues 368
Molecular Weight 39873.205
Theoretical pI 6.051
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence Not Available
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q83GY8
UniProtKB/Swiss-Prot Entry Name DXR_TROWT
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID Not Available
References
General References
  1. Raoult D, Ogata H, Audic S, Robert C, Suhre K, Drancourt M, Claverie JM: Tropheryma whipplei Twist: a human pathogenic Actinobacteria with a reduced genome. Genome Res. 2003 Aug;13(8):1800-9. doi: 10.1101/gr.1474603. [PubMed:12902375 ]