Human Metabolome Database: Showing Protein Myosin-IXa (HMDBP10964)

Identification Biological properties Gene properties Protein properties External links References XML Show 9288 metabolites

Identification

HMDB Protein ID

HMDBP10964

Secondary Accession Numbers

17278

Name

Myosin-IXa

Synonyms

Unconventional myosin-9a

Gene Name

MYO9A

Protein Type

Unknown

Biological Properties

General Function

Involved in motor activity

Specific Function

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Regulates Rho activity in neurons, has a role in the regulation of neuronal morphology and function

Pathways

Not Available

Reactions

Not Available

GO Classification

Component
myosin complex
cell part
macromolecular complex
protein complex
intracellular
Function
binding
catalytic activity
hydrolase activity
motor activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
nucleoside-triphosphatase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
pyrophosphatase activity
Process
biological regulation
regulation of biological process
regulation of cellular process
signal transduction
intracellular signaling pathway
signaling
signaling pathway

Cellular Location

Membrane
Single-pass membrane protein (Potential)

Gene Properties

Chromosome Location

Chromosome:1

Locus

15q22-q23

SNPs

MYO9A

Gene Sequence

>7647 bp
ATGAATATAAATGATGGAGGAAGACGACGCTTTGAAGATAATGAACATACATTACGGATA
TATCCTGGGGCTATTTCAGAAGGGACAATCTACTGTCCGATTCCTGCCAGAAAAAACTCC
ACAGCTGCTGAGGTGATTGAGTCTCTTATAAACAAACTTCATCTTGACAAAACAAAATGT
TATGTTCTAGCAGAGGTAAAGGAATTTGGTGGAGAAGAATGGATTCTCAATCCAACAGAT
TGTCCAGTTCAGCGAATGATGCTGTGGCCCCGAATGGCTCTGGAAAATCGCTTAAGTGGA
GAGGACTACCGCTTCCTTCTGAGAGAGAAAAACCTTGATGGATCAATCCATTATGGTAGC
CTGCAGTCATGGCTACGGGTAACAGAAGAACGTCGCAGGATGATGGAACGGGGTTTTCTT
CCACAGCCTCAACAGAAAGACTTTGATGATTTATGTAGTTTACCTGATTTGAATGAGAAA
ACTCTCTTAGAAAACCTACGAAATCGCTTTAAGCATGAAAAAATTTATACCTATGTTGGC
AGTATTCTAATAGTTATTAACCCATTCAAGTTTCTTCCTATTTATAACCCCAAATATGTC
AAAATGTATGATAACCACCAACTGGGAAAACTTGAGCCCCACATTTATGCTGTGGCTGAT
GTAGCTTATCATGCCATGCTTCAGCGCAAAAAGAATCAGTGCATCGTGATTTCAGGAGAG
AGTGGTTCTGGGAAGACTCAAAGCACAAACTTTCTTATTCACCACCTTACTGCTCTCAGT
CAGAAAGGATTTGCCAGTGGAGTAGAACAGATTATTCTTGGAGCTGGACCAGTACTTGAG
GCCTTTGGAAATGCAAAGACAGCTCATAATAACAATTCAAGTCGTTTTGGGAAGTTTATT
CAAGTAAATTACCAGGAAACAGGCACTGTACTTGGTGCCTATGTTGAAAAATATCTACTG
GAGAAGTCCAGACTCGTTTATCAGGAGCATAATGAACGGAACTATCATGTATTCTATTAC
CTCCTGGCAGGAGCAAGTGAAGATGAGAGATCAGCATTCCATCTTAAGCAACCAGAGGAA
TATCATTATCTCAATCAGATAACAAAGAAACCCCTCAGACAGAGCTGGGATGATTATTGC
TATGACTCTGAGCCGGATTGCTTCACGGTGGAAGGAGAAGATTTGAGACATGACTTTGAG
CGCCTACAACTTGCCATGGAAATGGTAGGATTTCTTCCCAAGACACGAAGACAGATTTTC
TCTCTTCTCTCAGCCATACTACATTTGGGTAATATCTGTTACAAAAAGAAGACATACCGG
GATGACTCCATTGATATCTGTAATCCTGAAGTTCTGCCTATTGTCTCAGAATTATTAGAG
GTTAAAGAAGAGATGCTATTTGAAGCATTAGTTACAAGGAAGACGGTGACAGTGGGAGAA
AAGCTTATTTTGCCATACAAGTTGGCAGAGGCTGTGACAGTGAGGAACTCCATGGCTAAG
TCTCTGTATAGTGCCCTGTTTGACTGGATAGTTTTTCGAATTAATCATGCACTTCTGAAT
AGTAAAGATTTAGAGCATAATACCAAGACATTGTCTATTGGTGTTCTTGATATTTTTGGG
TTTGAAGATTATGAAAATAACAGCTTTGAACAGTTCTGTATTAATTTTGCTAATGAACGT
TTACAGCACTACTTTAATCAGCATATCTTTAAATTGGAACAAGAGGAATATAGAACTGAA
GGTATCAGCTGGCACAACATAGATTACATTGATAATACCTGCTGCATAAATCTTATTAGC
AAAAAACCAACAGGACTGCTTCATCTTTTGGATGAAGAAAGCAACTTTCCACAGGCTACA
AATCAAACATTGCTAGACAAGTTTAAGCATCAACATGAAGATAATTCTTACATCGAATTT
CCAGCCGTGATGGAGCCTGCTTTCATTATAAAACATTATGCTGGAAAAGTAAAATATGGG
GTAAAGGATTTCCGGGAAAAAAATACAGATCATATGCGCCCAGACATTGTAGCTCTTCTG
AGAAGCAGCAAGAATGCATTTATCTCTGGGATGATTGGAATTGATCCTGTAGCTGTTTTC
CGATGGGCAATTCTCCGAGCTTTTTTCAGAGCCATGGTTGCTTTCAGGGAAGCTGGGAAA
AGAAACATTCACAGAAAAACTGGACATGATGATACAGCGCCATGTGCAATTTTGAAAAGT
ATGGATAGTTTTAGCTTTCTCCAACACCCAGTCCACCAGAGGAGCTTAGAGATTCTGCAG
AGATGCAAGGAAGAGAAGTACAGTATAACCCGGAAAAATCCCAGAACACCTCTTTCTGAT
CTCCAGGGCATGAATGCTCTAAATGAAAAAAACCAACATGATACATTTGATATTGCCTGG
AATGGCAGAACTGGGATTCGCCAGAGCAGACTATCAAGTGGCACCTCCTTGCTTGATAAA
GATGGAATATTTGCTAATTCAACTAGCAGCAAACTCCTGGAGAGAGCCCATGGAATTCTC
ACGAGAAACAAAAATTTCAAATCCAAGCCTGCCCTTCCAAAGCACTTGCTAGAAGTAAAT
TCTTTAAAGCACCTGACAAGACTGACACTACAAGATCGCATTACCAAGTCTCTTCTTCAT
TTACACAAGAAGAAAAAACCTCCCAGCATCAGTGCCCAGTTTCAGGCATCATTAAGCAAG
CTAATGGAAACACTTGGTCAAGCAGAACCATATTTTGTAAAATGCATTCGCTCTAATGCT
GAAAAGCTGCCCTTAAGGTTCAGTGATGTCTTGGTACTTAGACAGCTTCGATACACCGGG
ATGCTGGAAACAGTTCGAATTCGCCAATCAGGATACAGCTCCAAATATTCTTTCCAGGAT
TTTGTGAGCCACTTCCATGTACTTCTTCCCCGAAATATTATTCCATCCAAATTTAACATT
CAGGATTTCTTCAGGAAAATAAATCTTAATCCAGATAATTATCAAGTTGGAAAAACCATG
GTCTTTCTAAAGGAGCAGGAACGACAGCACTTACAAGATCTGCTTCACCAAGAGGTGCTC
CGCAGAATCATATTGTTGCAGCGATGGTTCAGGGTCTTGCTGTGTAGGCAGCATTTCCTC
CATCTGAGACAAGCATCTGTTATTATCCAGAGATTCTGGAGGAATTACCTAAATCAGAAG
CAAGTCAGAGATGCAGCTGTGCAGAAGGATGCTTTTGTTATGGCTAGTGCAGCTGCTCTT
CTCCAAGCTTCCTGGCGTGCTCACTTAGAGAGGCAGCGGTACTTGGAGTTACGGGCTGCA
GCCATCGTTATCCAGCAGAAATGGAGAGATTACTATAGGCGCAGGCACATGGCTGCTATT
TGCATACAAGCAAGATGGAAAGCCTACAGGGAAAGTAAAAGGTACCAAGAACAAAGGAAA
AAAATTATCCTTTTGCAATCAACATGTAGAGGATTCAGAGCAAGACAAAGATTTAAAGCT
TTAAAAGAACAAAGGCTAAGAGAAACAAAGCCAGAAGTTGGATTGGTGAATATTAAGGGA
TATGGATCTCTGGAAATTCAGGGTTCAGACCCTTCAGGATGGGAGGATTGTTCTTTTGAC
AACAGAATAAAAGCCATAGAGGAATGTAAATCTGTAATAGAGAGTAATCGAATTAGCCGT
GAAAGTTCAGTGGACTGCTTGAAGGAGTCACCAAACAAGCAGCAGGAGAGAGCCCAAAGC
CAGAGTGGTGTGGACTTGCAGGAAGATGTGCTTGTAAGAGAGAGACCCAGATCCTTGGAG
GATCTCCATCAGAAAAAAGTAGGCCGGGCTAAGAGAGAAAGTAGGAGAATGAGAGAACTA
GAGCAAGCTATATTTAGCTTAGAATTGCTGAAAGTTCGTTCTCTTGGTGGTATTTCTCCT
TCAGAGGATCGCAGATGGTCTACAGAATTGGTGCCTGAAGGCCTTCAGTCTCCACGGGGT
ACACCTGATAGTGAGAGCTCTCAAGGAAGCTTGGAACTTCTGAGCTATGAGGAAAGCCAA
AAGAGCAAACTAGAGTCTGTCATTTCAGATGAAGGAGACTTGCAGTTTCCATCACCTAAG
ATATCCAGCAGTCCAAAATTTGATTCACGGGACAATGCCCTCAGTGCCTCAAATGAGACT
AGCAGTGCAGAGCATTTGAAGGATGGAACTATGAAGGAAATGGTGGTCTGCAGTTCTGAG
TCTATTACCTGTAAACCACAGCTGAAAGACTCCTTCATTTCAAATAGTCTACCTACTTTT
TTTTATATCCCCCAACAAGACCCACTGAAAACAAATTCCCAACTAGACACAAGTATCCAA
AGAAACAAACTATTGGAAAATGAAGACACAGCGGGGGAAGCTCTTACTTTGGATATCAAC
AGGGAAACTAGAAGGTATCACTGCTCAGGAAAAGATCAGATTGTTCCTTCTTTGAATACA
GAGTCTTCTAATCCTGTGCTTAAGAAGTTAGAAAAGCTAAACACTGAGAAGGAAGAAAGG
CAAAAACAGTTGCAGCAACAGAATGAAAAAGAGATGATGGAACAGATTCGCCAGCAAACA
GATATTTTAGAGAAGGAGCGCAAAGCCTTCAAGACAATTGAAAAGCCAAGAATTGGAGAG
TGTTTGGTGGCACCATCTTCCTATCAGTCAAAGCAAAGAGTAGAGAGGCCATCCTCTCTC
CTCAGCTTAAATACCTCAAATAAGGGAGAACTTAATGTACTGGGGTCCCTATCATTAAAA
GATGCAGCTCTTGCCCAAAAAGACAGTTCCTCTGCTCACTTACCCCCAAAGGACCGACCT
GTCACCGTGTTCTTTGAAAGAAAAGGAAGTCCATGCCAATCTAGTACTGTCAAGGAATTA
TCCAAGACAGACAGAATGGGCACCCAGCTGAATGTAGCCTGTAAACTCTCAAATAATCGC
ATTTCAAAAAGAGAACACTTTAGGCCAACTCAGTCTTACAGCCACAATTCTGATGACCTT
TCCAGAGAGGGAAATGCTAGGCCCATTTTCTTCACTCCAAAGGACAATATGAGTATTCCC
CTTGTCAGCAAAGAAGCCTTAAACAGTAAAAATCCTCAACTCCATAAAGAAGATGAACCA
GCATGGAAACCTGTGAAGTTAGCTGGGCCAGGCCAAAGAGAGACATCACAGCGATTTTCG
TCAGTTGATGAACAAGCAAAACTTCATAAGACTATGTCTCAAGGAGAGATTACCAAGTTG
GCAGTGAGACAGAAGGCTTCAGATTCAGATATAAGACCTCAGAGAGCTAAGATGAGATTC
TGGGCCAAAGGGAAACAAGGGGAGAAGAAGACTACCAGAGTGAAACCTACTACCCAGTCA
GAGGTTTCGCCACTCTTTGCAGGCACAGATGTGATTCCAGCTCATCAGTTTCCAGATGAA
TTAGCTGCATATCACCCAACACCTCCTTTGAGCCCAGAACTGCCCGGCAGTTGCCGGAAG
GAATTCAAAGAGAACAAAGAACCTTCTCCAAAGGCTAAGCGCAAGCGAAGTGTGAAGATT
AGCAACGTGGCTTTGGATTCTATGCATTGGCAAAATGACTCTGTCCAGATCATAGCAAGT
GTCAGTGATTTAAAAAGCATGGATGAATTTCTTCTGAAAAAGGTGAATGACCTAGATAAT
GAAGACAGCAAGAAGGATACACTAGTGGATGTTGTATTTAAAAAAGCCCTGAAGGAATTT
CGGCAGAATATCTTCAGCTTTTATTCATCTGCATTGGCGATGGATGATGGGAAAAGCATA
CGGTATAAAGACCTCTATGCACTATTTGAACAGATTCTGGAAAAGACGATGAGGCTTGAG
CAGCGTGATTCACTGGGTGAATCTCCAGTGAGAGTTTGGGTCAACACTTTTAAAGTGTTT
TTAGATGAATATATGAATGAATTCAAGACTTCAGATTGCACAGCCACAAAGGTGCCAAAA
ACAGAAAGAAAGAAAAGAAGGAAAAAGGAAACTGATTTGGTGGAAGAACACAATGGTCAC
ATCTTTAAAGCCACCCAATATAGCATCCCTACATACTGTGAATACTGTTCTTCTTTGATA
TGGATAATGGACCGAGCCTCTGTTTGCAAATTATGCAAGTATGCTTGCCATAAGAAGTGC
TGTCTGAAAACCACAGCCAAGTGCTCTAAAAAGTATGATCCAGAGCTGTCATCTCGACAA
TTTGGGGTTGAACTGTCCCGTTTGACCAGTGAAGACCGAACTGTTCCTTTAGTAGTGGAA
AAGCTCATAAACTACATTGAAATGCATGGACTGTATACAGAAGGTATTTATCGAAAGTCT
GGTTCGACTAATAAAATCAAGGAGCTTCGGCAGGGTCTAGATACAGATGCTGAGAGTGTA
AATCTAGATGACTATAACATACACGTCATTGCAAGTGTATTCAAACAATGGCTTCGAGAT
TTGCCCAATCCTCTCATGACCTTTGAACTCTATGAGGAATTTCTTCGAGCTATGGGCCTT
CAGGAGAGGAAGGAGACAATCCGTGGTGTATACTCTGTGATTGATCAACTCTCCCGAACT
CATCTCAATACACTGGAACGCCTCATCTTTCATCTAGTCAGGATTGCTCTGCAGGAAGAC
ACTAATCGAATGTCTGCTAATGCTTTGGCCATTGTGTTTGCGCCCTGCATTCTCCGCTGC
CCTGACACCACTGACCCACTACAAAGTGTACAGGACATCAGTAAGACTACCACTTGTGTG
GAACTGATTGTTGTGGAACAAATGAATAAATACAAGGCTCGTCTCAAAGATATCAGTAGC
TTGGAATTTGCTGAGAATAAGGCAAAGACCAGGTTGTCACTGATTCGTAGATCAATGGGA
AAGGGGCGTATTCGTCGAGGAAACTATCCAGGTCCATCGTCTCCTGTTGTAGTTCGGTTG
CCTTCTGTGTCTGATGTCTCAGAGGAGACCTTGACTAGTGAGGCAGCCATGGAGACTGAC
ATCACAGAACAGCAGCAAGCAGCTATGCAGCAGGAGGAGAGAGTACTGACTGAGCAGATT
GAGAACCTACAGAAGGAGAAGGAGGAGCTAACATTTGAGATGCTTGTACTGGAACCCCGT
GCCTCTGATGATGAAACCCTTGAGTCTGAGGCCTCCATTGGGACTGCTGATAGCTCAGAG
AATTTGAATATGGAGTCTGAATATGCTATCTCTGAGAAATCAGAAAGAAGCTTAGCCCTT
AGCTCCCTGAAGACAGCTGGCAAGTCTGAACCTTCCAGCAAGTTGCGAAAGCAACTTAAA
AAGCAGCAAGACTCTTTAGATGTCGTGGACTCTTCGGTCTCCTCTTTATGTCTGTCTAAC
ACGGCATCATCTCATGGGACCAGAAAACTATTTCAGATTTATTCCAAATCTCCATTCTAC
CGAGCTGCCTCAGGTAATGAGGCCCTGGGAATGGAAGGACCATTGGGCCAGACCAAATTC
CTGGAAGACAAGCCTCAGTTCATCAGCAGAGGAACCTTCAACCCGGAAAAGGGCAAACAA
AAATTAAAGAATGTGAAAAACTCACCTCAGAAAACCAAAGAGACCCCAGAGGGGACAGTC
ATGTCTGGCCGCAGAAAAACTGTGGACCCAGACTGCACCTCCAACCAACAGCTAGCACTC
TTTGGAAATAATGAATTTATGGTCTGA

Protein Properties

Number of Residues

2548

Molecular Weight

292703.0

Theoretical pI

9.22

Pfam Domain Function

RA (PF00788 )
IQ (PF00612 )
Myosin_head (PF00063 )
RhoGAP (PF00620 )

Signals

None

Transmembrane Regions

175-195

Protein Sequence

>Myosin-IXa
MNINDGGRRRFEDNEHTLRIYPGAISEGTIYCPIPARKNSTAAEVIESLINKLHLDKTKC
YVLAEVKEFGGEEWILNPTDCPVQRMMLWPRMALENRLSGEDYRFLLREKNLDGSIHYGS
LQSWLRVTEERRRMMERGFLPQPQQKDFDDLCSLPDLNEKTLLENLRNRFKHEKIYTYVG
SILIVINPFKFLPIYNPKYVKMYDNHQLGKLEPHIYAVADVAYHAMLQRKKNQCIVISGE
SGSGKTQSTNFLIHHLTALSQKGFASGVEQIILGAGPVLEAFGNAKTAHNNNSSRFGKFI
QVNYQETGTVLGAYVEKYLLEKSRLVYQEHNERNYHVFYYLLAGASEDERSAFHLKQPEE
YHYLNQITKKPLRQSWDDYCYDSEPDCFTVEGEDLRHDFERLQLAMEMVGFLPKTRRQIF
SLLSAILHLGNICYKKKTYRDDSIDICNPEVLPIVSELLEVKEEMLFEALVTRKTVTVGE
KLILPYKLAEAVTVRNSMAKSLYSALFDWIVFRINHALLNSKDLEHNTKTLSIGVLDIFG
FEDYENNSFEQFCINFANERLQHYFNQHIFKLEQEEYRTEGISWHNIDYIDNTCCINLIS
KKPTGLLHLLDEESNFPQATNQTLLDKFKHQHEDNSYIEFPAVMEPAFIIKHYAGKVKYG
VKDFREKNTDHMRPDIVALLRSSKNAFISGMIGIDPVAVFRWAILRAFFRAMVAFREAGK
RNIHRKTGHDDTAPCAILKSMDSFSFLQHPVHQRSLEILQRCKEEKYSITRKNPRTPLSD
LQGMNALNEKNQHDTFDIAWNGRTGIRQSRLSSGTSLLDKDGIFANSTSSKLLERAHGIL
TRNKNFKSKPALPKHLLEVNSLKHLTRLTLQDRITKSLLHLHKKKKPPSISAQFQASLSK
LMETLGQAEPYFVKCIRSNAEKLPLRFSDVLVLRQLRYTGMLETVRIRQSGYSSKYSFQD
FVSHFHVLLPRNIIPSKFNIQDFFRKINLNPDNYQVGKTMVFLKEQERQHLQDLLHQEVL
RRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKDAFVMASAAAL
LQASWRAHLERQRYLELRAAAIVIQQKWRDYYRRRHMAAICIQARWKAYRESKRYQEQRK
KIILLQSTCRGFRARQRFKALKEQRLRETKPEVGLVNIKGYGSLEIQGSDPSGWEDCSFD
NRIKAIEECKSVIESNRISRESSVDCLKESPNKQQERAQSQSGVDLQEDVLVRERPRSLE
DLHQKKVGRAKRESRRMRELEQAIFSLELLKVRSLGGISPSEDRRWSTELVPEGLQSPRG
TPDSESSQGSLELLSYEESQKSKLESVISDEGDLQFPSPKISSSPKFDSRDNALSASNET
SSAEHLKDGTMKEMVVCSSESITCKPQLKDSFISNSLPTFFYIPQQDPLKTNSQLDTSIQ
RNKLLENEDTAGEALTLDINRETRRYHCSGKDQIVPSLNTESSNPVLKKLEKLNTEKEER
QKQLQQQNEKEMMEQIRQQTDILEKERKAFKTIEKPRIGECLVAPSSYQSKQRVERPSSL
LSLNTSNKGELNVLGSLSLKDAALAQKDSSSAHLPPKDRPVTVFFERKGSPCQSSTVKEL
SKTDRMGTQLNVACKLSNNRISKREHFRPTQSYSHNSDDLSREGNARPIFFTPKDNMSIP
LVSKEALNSKNPQLHKEDEPAWKPVKLAGPGQRETSQRFSSVDEQAKLHKTMSQGEITKL
AVRQKASDSDIRPQRAKMRFWAKGKQGEKKTTRVKPTTQSEVSPLFAGTDVIPAHQFPDE
LAAYHPTPPLSPELPGSCRKEFKENKEPSPKAKRKRSVKISNVALDSMHWQNDSVQIIAS
VSDLKSMDEFLLKKVNDLDNEDSKKDTLVDVVFKKALKEFRQNIFSFYSSALAMDDGKSI
RYKDLYALFEQILEKTMRLEQRDSLGESPVRVWVNTFKVFLDEYMNEFKTSDCTATKVPK
TERKKRRKKETDLVEEHNGHIFKATQYSIPTYCEYCSSLIWIMDRASVCKLCKYACHKKC
CLKTTAKCSKKYDPELSSRQFGVELSRLTSEDRTVPLVVEKLINYIEMHGLYTEGIYRKS
GSTNKIKELRQGLDTDAESVNLDDYNIHVIASVFKQWLRDLPNPLMTFELYEEFLRAMGL
QERKETIRGVYSVIDQLSRTHLNTLERLIFHLVRIALQEDTNRMSANALAIVFAPCILRC
PDTTDPLQSVQDISKTTTCVELIVVEQMNKYKARLKDISSLEFAENKAKTRLSLIRRSMG
KGRIRRGNYPGPSSPVVVRLPSVSDVSEETLTSEAAMETDITEQQQAAMQQEERVLTEQI
ENLQKEKEELTFEMLVLEPRASDDETLESEASIGTADSSENLNMESEYAISEKSERSLAL
SSLKTAGKSEPSSKLRKQLKKQQDSLDVVDSSVSSLCLSNTASSHGTRKLFQIYSKSPFY
RAASGNEALGMEGPLGQTKFLEDKPQFISRGTFNPEKGKQKLKNVKNSPQKTKETPEGTV
MSGRRKTVDPDCTSNQQLALFGNNEFMV

External Links

GenBank ID Protein

156119615

UniProtKB/Swiss-Prot ID

B2RTY4

UniProtKB/Swiss-Prot Entry Name

MYO9A_HUMAN

PDB IDs

Not Available

GenBank Gene ID

GeneCard ID

GenAtlas ID

HGNC ID

References

General References

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