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Showing metabocard for Cinnamaldehyde (HMDB0003441)

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Record Information
Version5.0
StatusDetected but not Quantified
Creation Date2006-08-12 20:46:08 UTC
Update Date2023-02-21 17:16:40 UTC
HMDB IDHMDB0003441
Secondary Accession Numbers
  • HMDB03441
Metabolite Identification
Common NameCinnamaldehyde
DescriptionCinnamaldehyde is the aldehyde that gives cinnamon its flavor and odor. Cinnamaldehyde occurs naturally in the bark of cinnamon trees and other species of the genus Cinnamomum like camphor and cassia. These trees are the natural source of cinnamon, and the essential oil of cinnamon bark is about 90% cinnamaldehyde. Cinnamaldehyde is also used as a fungicide. Proven effective on over 40 different crops, cinnamaldehyde is typically applied to the root systems of plants. Its low toxicity and well-known properties make it ideal for agriculture. To a lesser extent, cinnamaldehyde is an effective insecticide, and its scent is also known to repel animals like cats and dogs. Cinnamaldehyde is also known as a corrosion inhibitor for steel and other ferrous alloys in corrosive fluids. It can be used in combination with additional components such as dispersing agents, solvents and other surfactants. Concentrated cinnamaldehyde is a skin irritant, and the chemical is toxic in large doses, but no agencies suspect the compound is a carcinogen or poses a long-term health hazard. Most cinnamaldehyde is excreted in urine as cinnamic acid, an oxidized form of cinnamaldehyde.
Structure
Data?1676999800
MOL3D MOLSDF3D SDFPDB3D PDBSMILESInChI

MOL for HMDB0003441 (Cinnamaldehyde)


  Mrv1652309272007362D          

 10 10  0  0  0  0            999 V2000
10000.004810000.8102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10000.720510000.3998    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10001.434110000.8102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10002.149810000.3998    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9999.290210000.3987    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9998.575810000.8111    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9997.861210000.3986    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9997.8612 9999.5736    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9998.5757 9999.1611    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9999.2902 9999.5736    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10  5  1  0  0  0  0
  1  5  1  0  0  0  0
M  END
Download

3D MOL for HMDB0003441 (Cinnamaldehyde)

HMDB0003441
     RDKit          3D
Cinnamaldehyde
 18 18  0  0  0  0  0  0  0  0999 V2000
   -4.3723    1.1333   -0.3388 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5617    0.1906   -0.1895 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1386    0.5195   -0.1177 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3077   -0.4804    0.0386 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1274   -0.2596    0.1217 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9688   -1.3768    0.2900 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3210   -1.1758    0.3690 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8361    0.0997    0.2841 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0154    1.1787    0.1209 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6417    1.0011    0.0381 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9112   -0.8234   -0.1176 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8467    1.5494   -0.1952 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6796   -1.5168    0.1111 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5539   -2.3601    0.3542 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9801   -2.0196    0.4978 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9264    0.2347    0.3503 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4171    2.2052    0.0516 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0299    1.9001   -0.0926 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
 10  5  1  0
  2 11  1  0
  3 12  1  0
  4 13  1  0
  6 14  1  0
  7 15  1  0
  8 16  1  0
  9 17  1  0
 10 18  1  0
M  END
Download

3D SDF for HMDB0003441 (Cinnamaldehyde)


  Mrv1652309272007362D          

 10 10  0  0  0  0            999 V2000
10000.004810000.8102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10000.720510000.3998    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10001.434110000.8102    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
10002.149810000.3998    0.0000 O   0  0  0  0  0  0  0  0  0  0  0  0
 9999.290210000.3987    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9998.575810000.8111    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9997.861210000.3986    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9997.8612 9999.5736    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9998.5757 9999.1611    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
 9999.2902 9999.5736    0.0000 C   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0  0  0  0
  2  3  1  0  0  0  0
  3  4  2  0  0  0  0
  5  6  2  0  0  0  0
  6  7  1  0  0  0  0
  7  8  2  0  0  0  0
  8  9  1  0  0  0  0
  9 10  2  0  0  0  0
 10  5  1  0  0  0  0
  1  5  1  0  0  0  0
M  END
> <DATABASE_ID>
HMDB0003441

> <DATABASE_NAME>
hmdb

> <SMILES>
O=C\C=C\C1=CC=CC=C1

> <INCHI_IDENTIFIER>
InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+

> <INCHI_KEY>
KJPRLNWUNMBNBZ-QPJJXVBHSA-N

> <FORMULA>
C9H8O

> <MOLECULAR_WEIGHT>
132.1592

> <EXACT_MASS>
132.057514878

> <JCHEM_ACCEPTOR_COUNT>
1

> <JCHEM_ATOM_COUNT>
18

> <JCHEM_AVERAGE_POLARIZABILITY>
14.476246951483136

> <JCHEM_BIOAVAILABILITY>
1

> <JCHEM_DONOR_COUNT>
0

> <JCHEM_FORMAL_CHARGE>
0

> <JCHEM_GHOSE_FILTER>
0

> <JCHEM_IUPAC>
(2E)-3-phenylprop-2-enal

> <ALOGPS_LOGP>
2.00

> <JCHEM_LOGP>
1.9774700076666665

> <ALOGPS_LOGS>
-2.51

> <JCHEM_MDDR_LIKE_RULE>
0

> <JCHEM_NUMBER_OF_RINGS>
1

> <JCHEM_PHYSIOLOGICAL_CHARGE>
0

> <JCHEM_PKA_STRONGEST_BASIC>
-4.439447314621728

> <JCHEM_POLAR_SURFACE_AREA>
17.07

> <JCHEM_REFRACTIVITY>
42.1345

> <JCHEM_ROTATABLE_BOND_COUNT>
2

> <JCHEM_RULE_OF_FIVE>
1

> <ALOGPS_SOLUBILITY>
4.09e-01 g/l

> <JCHEM_TRADITIONAL_IUPAC>
cinnamal

> <JCHEM_VEBER_RULE>
1

$$$$
Download

3D-SDF for HMDB0003441 (Cinnamaldehyde)

HMDB0003441
     RDKit          3D
Cinnamaldehyde
 18 18  0  0  0  0  0  0  0  0999 V2000
   -4.3723    1.1333   -0.3388 O   0  0  0  0  0  0  0  0  0  0  0  0
   -3.5617    0.1906   -0.1895 C   0  0  0  0  0  0  0  0  0  0  0  0
   -2.1386    0.5195   -0.1177 C   0  0  0  0  0  0  0  0  0  0  0  0
   -1.3077   -0.4804    0.0386 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.1274   -0.2596    0.1217 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.9688   -1.3768    0.2900 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.3210   -1.1758    0.3690 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.8361    0.0997    0.2841 C   0  0  0  0  0  0  0  0  0  0  0  0
    2.0154    1.1787    0.1209 C   0  0  0  0  0  0  0  0  0  0  0  0
    0.6417    1.0011    0.0381 C   0  0  0  0  0  0  0  0  0  0  0  0
   -3.9112   -0.8234   -0.1176 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.8467    1.5494   -0.1952 H   0  0  0  0  0  0  0  0  0  0  0  0
   -1.6796   -1.5168    0.1111 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.5539   -2.3601    0.3542 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.9801   -2.0196    0.4978 H   0  0  0  0  0  0  0  0  0  0  0  0
    3.9264    0.2347    0.3503 H   0  0  0  0  0  0  0  0  0  0  0  0
    2.4171    2.2052    0.0516 H   0  0  0  0  0  0  0  0  0  0  0  0
    0.0299    1.9001   -0.0926 H   0  0  0  0  0  0  0  0  0  0  0  0
  1  2  2  0
  2  3  1  0
  3  4  2  0
  4  5  1  0
  5  6  2  0
  6  7  1  0
  7  8  2  0
  8  9  1  0
  9 10  2  0
 10  5  1  0
  2 11  1  0
  3 12  1  0
  4 13  1  0
  6 14  1  0
  7 15  1  0
  8 16  1  0
  9 17  1  0
 10 18  1  0
M  END
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PDB for HMDB0003441 (Cinnamaldehyde)

HEADER    PROTEIN                                 27-SEP-20   NONE
TITLE     NULL                                                        
COMPND    NULL                                                        
SOURCE    NULL                                                        
KEYWDS    NULL                                                        
EXPDTA    NULL                                                        
AUTHOR    Marvin                                                      
REVDAT   1   27-SEP-20         0                                  
HETATM    1  C   UNK     0    8666.6768668.179   0.000  0.00  0.00           C+0
HETATM    2  C   UNK     0    8668.0128667.413   0.000  0.00  0.00           C+0
HETATM    3  C   UNK     0    8669.3448668.179   0.000  0.00  0.00           C+0
HETATM    4  O   UNK     0    8670.6808667.413   0.000  0.00  0.00           O+0
HETATM    5  C   UNK     0    8665.3428667.411   0.000  0.00  0.00           C+0
HETATM    6  C   UNK     0    8664.0088668.181   0.000  0.00  0.00           C+0
HETATM    7  C   UNK     0    8662.6748667.411   0.000  0.00  0.00           C+0
HETATM    8  C   UNK     0    8662.6748665.871   0.000  0.00  0.00           C+0
HETATM    9  C   UNK     0    8664.0088665.101   0.000  0.00  0.00           C+0
HETATM   10  C   UNK     0    8665.3428665.871   0.000  0.00  0.00           C+0
CONECT    1    2    5                                                       
CONECT    2    1    3                                                       
CONECT    3    2    4                                                       
CONECT    4    3                                                            
CONECT    5    6   10    1                                                  
CONECT    6    5    7                                                       
CONECT    7    6    8                                                       
CONECT    8    7    9                                                       
CONECT    9    8   10                                                       
CONECT   10    9    5                                                       
MASTER        0    0    0    0    0    0    0    0   10    0   20    0
END
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3D PDB for HMDB0003441 (Cinnamaldehyde)

COMPND    HMDB0003441
HETATM    1  O1  UNL     1      -4.372   1.133  -0.339  1.00  0.00           O  
HETATM    2  C1  UNL     1      -3.562   0.191  -0.190  1.00  0.00           C  
HETATM    3  C2  UNL     1      -2.139   0.520  -0.118  1.00  0.00           C  
HETATM    4  C3  UNL     1      -1.308  -0.480   0.039  1.00  0.00           C  
HETATM    5  C4  UNL     1       0.127  -0.260   0.122  1.00  0.00           C  
HETATM    6  C5  UNL     1       0.969  -1.377   0.290  1.00  0.00           C  
HETATM    7  C6  UNL     1       2.321  -1.176   0.369  1.00  0.00           C  
HETATM    8  C7  UNL     1       2.836   0.100   0.284  1.00  0.00           C  
HETATM    9  C8  UNL     1       2.015   1.179   0.121  1.00  0.00           C  
HETATM   10  C9  UNL     1       0.642   1.001   0.038  1.00  0.00           C  
HETATM   11  H1  UNL     1      -3.911  -0.823  -0.118  1.00  0.00           H  
HETATM   12  H2  UNL     1      -1.847   1.549  -0.195  1.00  0.00           H  
HETATM   13  H3  UNL     1      -1.680  -1.517   0.111  1.00  0.00           H  
HETATM   14  H4  UNL     1       0.554  -2.360   0.354  1.00  0.00           H  
HETATM   15  H5  UNL     1       2.980  -2.020   0.498  1.00  0.00           H  
HETATM   16  H6  UNL     1       3.926   0.235   0.350  1.00  0.00           H  
HETATM   17  H7  UNL     1       2.417   2.205   0.052  1.00  0.00           H  
HETATM   18  H8  UNL     1       0.030   1.900  -0.093  1.00  0.00           H  
CONECT    1    2    2
CONECT    2    3   11
CONECT    3    4    4   12
CONECT    4    5   13
CONECT    5    6    6   10
CONECT    6    7   14
CONECT    7    8    8   15
CONECT    8    9   16
CONECT    9   10   10   17
CONECT   10   18
END
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SMILES for HMDB0003441 (Cinnamaldehyde)

O=C\C=C\C1=CC=CC=C1
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INCHI for HMDB0003441 (Cinnamaldehyde)

InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
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View in JSmolView Stereo Labels
Synonyms
ValueSource
(e)-3-Phenyl-2-propenalChEBI
(e)-3-Phenyl-propenalChEBI
(e)-3-PhenylpropenalChEBI
(e)-Cinnamic aldehydeChEBI
(e)-Phenylvinyl aldehydeChEBI
3-PhenylacrylaldehydeChEBI
trans-Cinnamic aldehydeChEBI
(e)-CinnamaldehydeHMDB
(2E)-3-Phenyl-2-propenalHMDB
(2E)-3-PhenylacrylaldehydeHMDB
3-FenylpropenalHMDB
3-Phenyl-2-propen-1-alHMDB
3-Phenyl-2-propenaldehydeHMDB
3-PhenylacroleinHMDB
3-Phenylprop-2-enalHMDB
3-PhenylpropenalHMDB
BenzylideneacetaldehydeHMDB
beta-PhenylcroleinHMDB
CinnamalHMDB
Cinnamic aldehydeHMDB
Cinnamyl aldehydeHMDB
CinnamylaldehydeHMDB
CinnemaldehydeHMDB
trans-3-Phenyl-2-propenalHMDB
trans-CinnamaldehydeHMDB
trans-CinnamylaldehydeHMDB
beta-PhenylacroleinHMDB
SupercinnamaldehydeHMDB
trans-3-Phenylprop-2-enaldehydeHMDB
3-Phenylprop-2-enaldehydeHMDB
Cinnamic aldehyde, (e)-isomerHMDB
2E)-3-Phenyl-2-propenalPhytoBank
(E)-3-PhenylacroleinPhytoBank
(E)-3-Phenylprop-2-en-1-alPhytoBank
(E)-3-Phenylprop-2-enalPhytoBank
(E)-3-Phenylprop-2-enonePhytoBank
E-Cinnamyl aldehydePhytoBank
trans-3-PhenylpropenalPhytoBank
trans-BenzenepropenalPhytoBank
3-Phenyl-2-propenalPhytoBank
3-Phenyl-2-propene-1-alPhytoBank
Chemical FormulaC9H8O
Average Molecular Weight132.1592
Monoisotopic Molecular Weight132.057514878
IUPAC Name(2E)-3-phenylprop-2-enal
Traditional Namecinnamal
CAS Registry Number104-55-2
SMILES
O=C\C=C\C1=CC=CC=C1
InChI Identifier
InChI=1S/C9H8O/c10-8-4-7-9-5-2-1-3-6-9/h1-8H/b7-4+
InChI KeyKJPRLNWUNMBNBZ-QPJJXVBHSA-N
Chemical Taxonomy
Description Belongs to the class of organic compounds known as cinnamaldehydes. These are organic aromatic compounds containing a cinnamlaldehyde moiety, consisting of a benzene and an aldehyde group to form 3-phenylprop-2-enal.
KingdomOrganic compounds
Super ClassPhenylpropanoids and polyketides
ClassCinnamaldehydes
Sub ClassNot Available
Direct ParentCinnamaldehydes
Alternative Parents
Substituents
  • Cinnamaldehyde
  • Styrene
  • Benzenoid
  • Monocyclic benzene moiety
  • Enal
  • Alpha,beta-unsaturated aldehyde
  • Organic oxygen compound
  • Organic oxide
  • Hydrocarbon derivative
  • Organooxygen compound
  • Carbonyl group
  • Aldehyde
  • Aromatic homomonocyclic compound
Molecular FrameworkAromatic homomonocyclic compounds
External Descriptors
Ontology
Physiological effect
Organoleptic effect
Disposition
Biological locationRoute of exposureSource
ProcessNot Available
Role
Biological roleIndustrial application
Physical Properties
StateLiquid
Experimental Molecular Properties
PropertyValueReference
Melting Point-7.5 °CNot Available
Boiling Point248.00 °C. @ 760.00 mm HgThe Good Scents Company Information System
Water Solubility1.42 mg/mL at 25 °CNot Available
LogP1.90HANSCH,C ET AL. (1995)
Experimental Chromatographic Properties

Experimental Collision Cross Sections

Adduct TypeData SourceCCS Value (Å2)Reference
[M+H]+Baker134.25130932474
[M+H]+Not Available134.251http://allccs.zhulab.cn/database/detail?ID=AllCCS00002051
Predicted Molecular Properties
PropertyValueSource
Water Solubility0.41 g/LALOGPS
logP2ALOGPS
logP1.98ChemAxon
logS-2.5ALOGPS
pKa (Strongest Basic)-4.4ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count1ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area17.07 ŲChemAxon
Rotatable Bond Count2ChemAxon
Refractivity42.13 m³·mol⁻¹ChemAxon
Polarizability14.48 ųChemAxon
Number of Rings1ChemAxon
BioavailabilityYesChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted Chromatographic Properties

Predicted Collision Cross Sections

PredictorAdduct TypeCCS Value (Å2)Reference
DarkChem[M+H]+131.8331661259
DarkChem[M-H]-127.69831661259
DeepCCS[M+H]+128.30130932474
DeepCCS[M-H]-124.80430932474
DeepCCS[M-2H]-162.04230932474
DeepCCS[M+Na]+137.40230932474
AllCCS[M+H]+127.032859911
AllCCS[M+H-H2O]+122.332859911
AllCCS[M+NH4]+131.332859911
AllCCS[M+Na]+132.632859911
AllCCS[M-H]-125.932859911
AllCCS[M+Na-2H]-127.532859911
AllCCS[M+HCOO]-129.232859911

Predicted Retention Times

Underivatized

Chromatographic MethodRetention TimeReference
Measured using a Waters Acquity ultraperformance liquid chromatography (UPLC) ethylene-bridged hybrid (BEH) C18 column (100 mm × 2.1 mm; 1.7 μmparticle diameter). Predicted by Afia on May 17, 2022. Predicted by Afia on May 17, 2022.5.58 minutes32390414
Predicted by Siyang on May 30, 202213.5968 minutes33406817
Predicted by Siyang using ReTip algorithm on June 8, 20226.98 minutes32390414
Fem_Long = Waters ACQUITY UPLC HSS T3 C18 with Water:MeOH and 0.1% Formic Acid2063.0 seconds40023050
Fem_Lipids = Ascentis Express C18 with (60:40 water:ACN):(90:10 IPA:ACN) and 10mM NH4COOH + 0.1% Formic Acid489.9 seconds40023050
Life_Old = Waters ACQUITY UPLC BEH C18 with Water:(20:80 acetone:ACN) and 0.1% Formic Acid197.9 seconds40023050
Life_New = RP Waters ACQUITY UPLC HSS T3 C18 with Water:(30:70 MeOH:ACN) and 0.1% Formic Acid327.3 seconds40023050
RIKEN = Waters ACQUITY UPLC BEH C18 with Water:ACN and 0.1% Formic Acid229.9 seconds40023050
Eawag_XBridgeC18 = XBridge C18 3.5u 2.1x50 mm with Water:MeOH and 0.1% Formic Acid566.8 seconds40023050
BfG_NTS_RP1 =Agilent Zorbax Eclipse Plus C18 (2.1 mm x 150 mm, 3.5 um) with Water:ACN and 0.1% Formic Acid645.4 seconds40023050
HILIC_BDD_2 = Merck SeQuant ZIC-HILIC with ACN(0.1% formic acid):water(16 mM ammonium formate)162.4 seconds40023050
UniToyama_Atlantis = RP Waters Atlantis T3 (2.1 x 150 mm, 5 um) with ACN:Water and 0.1% Formic Acid1264.0 seconds40023050
BDD_C18 = Hypersil Gold 1.9µm C18 with Water:ACN and 0.1% Formic Acid473.3 seconds40023050
UFZ_Phenomenex = Kinetex Core-Shell C18 2.6 um, 3.0 x 100 mm, Phenomenex with Water:MeOH and 0.1% Formic Acid1217.9 seconds40023050
SNU_RIKEN_POS = Waters ACQUITY UPLC BEH C18 with Water:ACN and 0.1% Formic Acid369.1 seconds40023050
RPMMFDA = Waters ACQUITY UPLC BEH C18 with Water:ACN and 0.1% Formic Acid383.2 seconds40023050
MTBLS87 = Merck SeQuant ZIC-pHILIC column with ACN:Water and :ammonium carbonate529.4 seconds40023050
KI_GIAR_zic_HILIC_pH2_7 = Merck SeQuant ZIC-HILIC with ACN:Water and 0.1% FA435.1 seconds40023050
Meister zic-pHILIC pH9.3 = Merck SeQuant ZIC-pHILIC column with ACN:Water 5mM NH4Ac pH9.3 and 5mM ammonium acetate in water78.3 seconds40023050

Predicted Kovats Retention Indices

Underivatized

MetaboliteSMILESKovats RI ValueColumn TypeReference
CinnamaldehydeO=C\C=C\C1=CC=CC=C11962.6Standard polar33892256
CinnamaldehydeO=C\C=C\C1=CC=CC=C11208.1Standard non polar33892256
CinnamaldehydeO=C\C=C\C1=CC=CC=C11226.2Semi standard non polar33892256
Spectra
Biological Properties
Cellular Locations
  • Membrane (predicted from logP)
Biospecimen Locations
  • Feces
Tissue Locations
  • Epidermis
  • Neuron
Pathways
Normal Concentrations
BiospecimenStatusValueAgeSexConditionReferenceDetails
FecesDetected but not QuantifiedNot QuantifiedAdult (>18 years old)Both
Normal		 details
Abnormal Concentrations
Not Available
Associated Disorders and Diseases
Disease ReferencesNone
Associated OMIM IDsNone
DrugBank IDNot Available
Phenol Explorer Compound IDNot Available
FooDB IDFDB030727
KNApSAcK IDC00002725
Chemspider ID553117
KEGG Compound IDC00903
BioCyc IDNot Available
BiGG IDNot Available
Wikipedia LinkCinnamaldehyde
METLIN ID6931
PubChem Compound637511
PDB IDNot Available
ChEBI ID16731
Food Biomarker OntologyNot Available
VMH IDNot Available
MarkerDB IDNot Available
Good Scents IDrw1092691
References
Synthesis ReferenceLiu, Xue-mei. Synthesis of cinnamaldehyde. Qufu Shifan Daxue Xuebao, Ziran Kexueban (2005), 31(2), 96-98.
Material Safety Data Sheet (MSDS)Download (PDF)
General References
  1. Bandell M, Story GM, Hwang SW, Viswanath V, Eid SR, Petrus MJ, Earley TJ, Patapoutian A: Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron. 2004 Mar 25;41(6):849-57. [PubMed:15046718 ]
  2. Muller G, Biering A, Graubaum K, Jeschkeit H, Neubert K, Kleine R, Klapperstuck M: [The PABA test]. Dtsch Z Verdau Stoffwechselkr. 1984;44(5):219-31. [PubMed:6334604 ]
  3. Smith CK, Moore CA, Elahi EN, Smart AT, Hotchkiss SA: Human skin absorption and metabolism of the contact allergens, cinnamic aldehyde, and cinnamic alcohol. Toxicol Appl Pharmacol. 2000 Nov 1;168(3):189-99. [PubMed:11042091 ]
  4. Smith CK, Cheung C, Elahi EN, Hotchkiss SA: High-performance liquid chromatography method for the quantification of non-radiolabelled cinnamic compounds in analytes derived from human skin absorption and metabolism experiments. J Chromatogr B Biomed Sci Appl. 2001 Jul 15;758(2):249-64. [PubMed:11486835 ]
  5. Bruze M, Johansen JD, Andersen KE, Frosch P, Lepoittevin JP, Rastogi S, Wakelin S, White I, Menne T: Deodorants: an experimental provocation study with cinnamic aldehyde. J Am Acad Dermatol. 2003 Feb;48(2):194-200. [PubMed:12582388 ]